What is the difference between Botox and Fillers?

17:17:51 28/06/2021

Botox and Filler injections are two popular non-surgical beauty methods today. However, beauty influences sometimes still have confusion about these two concepts. The following article below will tell you about the difference between Botox and Fillers, their uses as well as how these two active substances work and also introduce Botox injections to relax muscles and remove wrinkles at ROHTO AOHAL CLINIC.

Botox is a commonly used term in aesthetics, but not all customers have full knowledge of this active substance. Let's learn about the concept, uses and notes with ROHTO AOHAL CLINIC when using this beauty therapy!

What is Botox?

Botox is an active substance extracted from the bacterium Clostridium Botulinum and exists in liquid form. This active substance can be great for effective wrinkle removal and skin rejuvenation with only a small amount injected into the body.

Botox is based on the mechanism of locking nerve signals in injection areas. After the active substance Botox enters the skin, these nerve signals will be interrupted, the injected muscle area is temporarily paralyzed or inactivated. From there, the wrinkles will gradually fade and proceed to completely remove the wrinkles.

The use when injecting Botox

Botox injections are the choice of many people to treat dynamic wrinkles on the face. These are wrinkles that form when customers perform facial expressions such as frowning, laughing or when grinning, talking,…

Botox showed outstanding effect when used to treat glabellar lines, crow’s feet and the forehead lines.

Some notes when injecting Botox

According to studies by the American Society of Plastic Surgery (APS), the Botox injection method is considered safe. And statistics from the Association show that as many as 6.7 million people injected Botox in 2015.

However, when injecting Botox customers may still have some undesirable reactions. And this depends a lot on the doctor's injections technique as well as the dosage of the unit injected into the body. Therefore, customers must pay great attention and choose the right reputable aesthetic facility to perform the therapy

Some possible reactions to inject Botox:

  • Headache.
  • The feeling of dry mouth.
  • Swelling of the treatment area for a short time

Fillers - The active substance is widely used in aesthetics

If customers would like to understand "How do Botox and Fillers work" then it is necessary to fully learn about the concept, the use as well as the reaction that may occur when injecting fillers is essential.

What is Fillers?

Fillers is a group of substances used to inject into muscle areas beneath the surface of the skin to be treated, which fills the sunken skin areas.

Types of Fillers is commonly used today

  • Juvederm: This Fillers has a predominant composition of Hyaluronic Acid - naturally produced by the human's body. Juvederm is considered a benign active substance, which reduces possible reactions when injected Fillers.
  • Restylane: This is one of the safe natural substances, does not contain animal origin and will automatically biodegrade over time Therefore, Restylane is perfectly suited the human body
  • Sculptra: This substance has a main component of poly-L-lactic acid (PLLA), it is classified as a substance that stimulates the production and regeneration of collagen with a long-term effect, especially bringing the effect of "skin rejuvenation" maintained up to 2 years.
  • Radiesse: This substance immediately improves the surface of the skin after only one injection. Radiesse will help stimulate the body to produce collagen, regenerate and fill sunken skin areas.

Uses of Fillers Injections

How do Botox and Fillers work? By the difference in how it works and the effectiveness of the effect that indications for the treatment of signs of skin aging are also different. Among today's aesthetics, ROHTO AOHAL CLINIC is the choice favored by many customers because we put the safety factor of customers first.

  • Fill with concave scars, sunken skin.
  • Fill your lips with thin lips.
  • Fill the static wrinkles from the nose wing downwards.
  • Remove puffy eyes, wrinkles under the eyes.

Some notes when injecting Fillers

The Fillers injection method has been proven to be safe, but to avoid possible reactions, customers should choose reputable and professional aesthetic facilities in treatment. Among today's aesthetics, ROHTO AOHAL CLINIC is the choice favored by many customers because we put the safety factor of our customers first.

Some possible reactions when injecting Fillers:

  • The filler-injected skin may have red swelling or slight bruising.
  • Itching, rash or pimples in the injection area.
  • Appearance of dead skin cells due to decreased blood flow.

How are Botox vs Fillers different?

Besides cosmetic methods without surgery so currently you can use those active substances for beauty such as Botox and Fillers. Both types of active substances are proven safe for human’s health by the FDA (USA). Therefore, they allow the application of these products in the beauty industry.

However, a lot of people are confused between these two types because they offer similar uses. So what is Botox vs Fillers difference ? Let’s find out the criteria below with our experts. 


Botox has the full scientific name - botulinum toxin and is the trade name of the essence protein component extracted from a microorganism. This active substance has the effect of blocking neuro-muscle conduct transmission, reducing the activity of the muscles it governs.

Meanwhile, Fillers are specially formulated from many types such as hyaluronic acid, calcium hydroxyapatite, PLLA. This active substance is usually prescribed to fill static wrinkles (wrinkles caused by loss of tissue volume). In particular, the hyaluronic acid component in Fillers with 98% is physiological saline – a biological filler with a fairly high level of compatibility with the human body.

The subject of implementation

Filler injections bring a lot of effects in aesthetics, especially in the following cases below:

  • Fill out the sunken areas such as nasal grooves, cheeks, and temples,...

  • Enhance the physical features such as: help lengthen and sharpen the chin area, giving customers the desirable V-Line face, make the nose bridge higher and straighter, smoothing out any bump on the nose, and achieve fuller lips as well

  • Removing static wrinkles caused by the aging process.

Botox has the effect of preventing nerve signals from coming to the muscles, so it reduces the formation of wrinkles when the facial muscles move. Therefore, Botox is used when there is a need for:

  • Erase wrinkles: forehead wrinkles, crow's feet, frowns, rabbit wrinkles, gummy smile.

  • Face shaping (jaw slimming).

Implementation time and the duration of effect?

What is the difference between Botox and Filler in terms of execution time and duration of effect? Both Botox and Fillers can perform injections immediately after a qualified doctor's diagnosis. However, in some cases it is not recommended to take measures such as:

  • Cases of immunity with Botox, Fillers (extremely low efficiency).

  • Do not apply to women who are pregnant or breast-feeding to avoid harm to pregnancy and infant health.

  • Do not give injections for people with neurological disorders.

  • People with blood thinning diseases.

One difference between Botox and Fillers we easily notice when using is the duration of the effect. Fillers can maintain its ability to be active from 6 months to 2 years depending on each customer's lifestyle. While the active substance Botox only retains its use for 6 - 9 months.

How do Botox and Fillers work?

Botox or Fillers injections are both used  to beautify, remove wrinkles and rejuvenate the skin. However, these two active substances differ completely in the mechanism of action. Customers can refer to similarities and differences between the two methods in the table below:


Botox Injections Method

Fillers Injections Method

How it works

Inactivated the muscles in areas of skin with dynamic wrinkles by preventing nerve signals from transmitting to this muscle group.

Fill skin tissue with sunken skin, scars or static wrinkles.

The Result

After a few days

Right away

Effective maintenance time

6 - 9 months.

From 6 months to 2 years.

The Advantage

Beauty efficiency is quicker and more cost-effective when compared to surgical beauty methods.

The Disadvantage

Botox and Fillers injections have no permanent effect and must be re-injected if they want to maintain beauty results.


Botox injections and Filler injections are two beauty methods that are considered safe and are popular among aesthetics. The side effects of Botox and Filler are negligible and will not appear if the customer chooses the right reputable and quality aesthetic facility.

Relaxing muscle wrinkles removal therapy at ROHTO AOHAL CLINIC

After learning about the differences between Botox and Fillers, ROHTO AOHAL CLINIC would like to introduce Botox injections to relax muscles and remove wrinkles that are popular at the clinic.

ROHTO AOHAL CLINIC currently has 3 branches in Hanoi and Ho Chi Minh City. Clinic was established in Vietnam in 2015, under the management of Rohto-Mentholatum Vietnam, based on the cooperation between Rohto Pharmaceutical (a top cosmeceutical company with offices located in 150 countries around the globe) and AOHAL CLINIC (an acclaimed beauty clinic with more than 10 years of operation in Japan)

Beauty treatments at ROHTO AOHAL CLINIC ensure Japanese quality and standards.

For Botox injections that relax muscles and remove wrinkles, Botox will help facial muscles relax, paralyzing the contraction of facial muscle groups, thereby reducing and removing wrinkles.

6-step treatment of the process:

  • Step 1: Cleanse the face, prep the skin for treatment.

  • Step 2: Skin analysis with VISIA machine.

  • Step 3: Consultation with doctor. Our doctor will come up with a suitable dosage for each customer.

  • Step 4: Our therapist applies numbing cream on the skin area that will be injected.

  • Step 5: Our doctor performs the Botox injection

  • Step 6: Finish the treatment

Botox injections, in addition to reducing wrinkles, our clinic also applies to the following therapeutic purposes: relax the jaw muscles, shape the V-line face and treat sweating of the skin under the arms, hand and feet area.

Outstanding advantages when injecting Botox at ROHTO AOHAL CLINIC:

  • The process is quick, no downtime, and can be started to work immediately after the injection.

  • Use FDA-approved medication, which does not cause irritation and complications.

  • A team of highly skilled & experienced doctors and advisory dermatologists from Japan.

  • Commitment to fully comply with the dosage as recommended by the medical organization.

In addition to skin relax and wrinkle removal injections, we also offer injectable Fillers at ROHTO AOHAL CLINIC. Fillers is manufactured by two well-known brands, Restylane and Juvéderm, both FDA (USA) certified for safety.

Botox and Fillers injections are popular, cost-effective and painless beauty methods similar to having plastic surgery without facing the risks and complications that usually come with going under the knife.

If you are looking for a reputable non-surgical aesthetic address and are committed to quality, please contact ROHTO AOHAL CLINIC.


1st Location:

- Address: 02 Pham Dinh Toai, Ward 6, District 3, Ho Chi Minh City

- Phone: (028) 3930 9555

2nd Location:

- Address: 207/4 Nguyen Van Thu, Da Kao Ward, District 1, Ho Chi Minh City

- Phone: (028) 3827 9737

3rd Location:

- Address: 136 Trieu Viet Vuong, Nguyen Du Ward, Hai Ba Trung District, Ha Noi City

- Phone: (024) 3375 5588